This lecture will discuss the tools and tips that help you write your dissertation. It covers the key chapters and overall text organisation, as well as challenges that arise during the defense . The lecture is suitable for students in all stages of their doctorate, but is especially helpful for those who have started drafting chapters. The lecture is introduced by John Creemers , Director of the Doctoral School Biomedical Sciences, with some practical guidelines and tips specific for a PhD thesis at KU Leuven. What follows, is a preliminary overview of what you will learn.